Cefpirome as empirical treatment for febrile neutropenia in patients with hematologic malignancies.

نویسندگان

  • Gert Jan Timmers
  • Dannis G van Vuurden
  • Eleonora L Swart
  • Alberdina M Simoons-Smit
  • Peter C Huijgens
چکیده

Cefpirome, a fourth generation cephalosporin, was administered during 154 episodes of febrile neutropenia in 106 patients. We assessed the clinical efficacy of cefpirome and its activity against isolated pathogens in neutropenic patients with hematologic malignancies. In addition, the pharmacokinetics and optimal dosing regimen of cefpirome during neutropenia were investigated.

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عنوان ژورنال:
  • Haematologica

دوره 90 7  شماره 

صفحات  -

تاریخ انتشار 2005